Glyphosate, the active ingredient in the widely used weedkiller Roundup, has been previously linked to cases of cancer. Now researchers are finding evidence that chemicals in the herbicide may act as endocrine disruptors, interfering with the body’s hormones and leading to developmental and reproductive problems, and brain and immune system disruption.

The study titled “Glyphosate and the key characteristics of an endocrine disruptor: A Review,” published in the journal Chemosphere, is the first to consolidate the evidence on glyphosate as an endocrine-disrupting chemical. It follows studies published earlier this year that found glyphosate had an adverse impact on animals’ reproductive organs and threatened reproduction.

Dana Barr, professor at Emory University’s Rollins School of Public Health, said the evidence “overwhelmingly” indicates glyphosate has endocrine-disrupting properties. “It’s not necessarily unexpected since glyphosate has some structural similarities with many other endocrine-disrupting pesticides; however, it is more concerning because glyphosate use far surpasses pesticides,” he said.

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